|
KMID : 1035520230110040281
|
|
Brain Tumor Research and Treatment : BTRT
2023 Volume.11 No. 4 p.281 ~ p.288
|
|
|
Primary Intracranial Ewing Sarcoma With EWSR1-FLI1 Gene Translocation Mimicking a Meningioma and a Multidisciplinary Therapeutic Approach: A Case Report and Systematic Review of Literatures
|
|
Hyun Chang-Jun
Lee Yeon-Ju
Kang Ho
Park Hyun-Joo
Suh Koung-Jin
Choi Byung-Se
Choe Ghee-Young
Kim Chae-Yong
|
|
|
Abstract
|
|
|
|
Ewing sarcoma and peripheral primitive neuroectodermal tumor (ES/pPNET) is an undifferentiated malignant tumor that is most prevalent in children and young adults and often radiologically mimics a meningioma. A 38-year-old female patient visited our hospital with complaints of right-sided tinnitus, right hemiparesis, and imbalance. She underwent preoperative imaging and was subsequently diagnosed as having a meningioma on the petrous ridge. After partial resection, EWSR1-FLI1 gene fusion was confirmed, and she was diagnosed with ES/pPNET. The tumor was successfully treated using a multidisciplinary approach of adjuvant chemo- and radiotherapy. This case is noteworthy because it is an extremely rare case of an intracranial ES/pPNET, and it is worth sharing our clinical experience that the tumor was successfully treated through a multidisciplinary therapeutic approach even though complete resection was not achieved.
|
|
|
KEYWORD
|
|
|
Ewing sarcoma, Peripheral primitive neuroectodermal tumor, Meningioma, EWSR1, FLI1
|
|
|
FullTexts / Linksout information
|
|
|
|
|
|
Listed journal information
|
|
|
|